Breakthrough Science. Perfect Precision. Real ECZEMA Relief.
Experience first-of-its-kind eczema care: rigorously researched formulas powered by TPZ-01™, a patented enzyme that specifically targets Staph aureus, the bacteria behind flare-ups.
“If you’re not addressing Staph aureus on the skin, you’re not fully treating eczema.”
— Peter Lio, MD
Board-Certified Dermatologist
2.5x
more effective than a standard eczema treatment*
99.99%
of Staph aureus bacteria killed within 5 minutes**
*Based on a 2-week clinical trial of 24 adults with moderate to severe eczema comparing Hypothesis Eczema Precision Hydrogel to a product containing over-the-counter levels of colloidal oatmeal.
**Based on in vitro data of TPZ-01™enzyme
MEET
TPZ-O1™
Our Proprietary Enzyme
In a breakthrough for eczema care, our patented TPZ-01™ enzyme zeroes in on eczema-associated Staph aureus bacteria and eliminates them.
What you’ll see? Real daily relief that breaks the cycle of flare-ups and irritation so skin can finally heal.
MEET TPZ-O1™
Our Proprietary Enzyme
In a breakthrough for eczema care, our patented TPZ-01™ enzyme zeroes in on eczema-associated Staph aureus bacteria and eliminates them.
What you’ll see? Real daily relief that breaks the cycle of flare-ups and irritation so skin can finally heal.
2.5x
more effective than a standard eczema treatment*
99.99%
of Staph aureus bacteria killed within 5 minutes**
*Based on a 2-week clinical trial of 24 adults with moderate to severe eczema comparing Hypothesis Eczema Precision Hydrogel to a product containing over-the-counter levels of colloidal oatmeal.
**Based on in vitro data of TPZ-01™enzyme
ECZEMA + THE MICROBIOME
In a healthy skin microbiome, microorganisms live in balance and support skin health—but an eczema microbiome looks dramatically different.
Staph aureus bacteria on the skin drive eczema symptoms
The harmful bacteria Staph aureus can make up to 90% of the eczema microbiome, triggering flare-ups, itching, and skin barrier damage.
TPZ-01™ enzyme kills Staph aureus + preserves beneficial microbes
Unlike conventional eczema treatments, the TPZ-01™ enzyme addresses this root cause of eczema symptoms while preserving the skin’s protective microbiome.
Tested. Certified. Safe.
Our cutting-edge precision formulas have been rigorously tested and clinically validated for safety and efficacy.
Accepted by the National Eczema Association (NEA)
Certified Microbiome Friendly for Infants and Adults
EWG Verified®
Leaping Bunny Certified
Eczema Precision Hydrogel
Relieves irritation + itching from eczema
RESULTS
2.5x
more effective than a standard eczema treatment*
85%
reduction in eczema-associated Staph aureus bacteria on the skin*
100%
of participants saw reduced eczema symptoms within 2 weeks*
*Based on a 2-week clinical trial of 24 adults with moderate to severe eczema comparing Hypothesis Eczema Precision Hydrogel to a product containing over-the-counter levels of colloidal oatmeal.
Eczema Therapy Cream
Hydrates dry skin + restores the skin barrier
RESULTS
96%
said it nourished and improved dry skin*
91%
saw improved hydration for 24 hours after a single use*
100%
of participants saw immediate improvement in skin barrier function that lasted all day**
*Based on a 7-day clinical study of 34 adults with dry skin.
**Based on a clinical trial of 33 adults with damaged skin barriers.
Precision Healing Spray
Soothes flare-ups + calms eczema-prone skin
RESULTS
100%
100% of participants saw immediate improvement in skin barrier function that lasted all day*
97%
experienced instant improvement in hydration**
95%
agreed the spray is non-irritating and gentle on skin**
*Based on a clinical trial of 33 adults with damaged skin barriers.
**Based on a 7-day clinical study of 34 adults with dry skin.
Eczema Precision Hydrogel
Relieves irritation + itching from eczema
RESULTS
2.5x
more effective than a standard eczema treatment*
85%
reduction in eczema-associated Staph aureus bacteria on the skin*
100%
of participants saw reduced eczema symptoms within 2 weeks*
*Based on a 2-week clinical trial of 24 adults with moderate to severe eczema comparing Hypothesis Eczema Precision Hydrogel to a product containing over-the-counter levels of colloidal oatmeal.
Eczema Therapy Cream
Hydrates dry skin + restores the skin barrier
RESULTS
96%
said it nourished and improved dry skin*
91%
saw improved hydration for 24 hours after a single use*
100%
of participants saw immediate improvement in skin barrier function that lasted all day**
*Based on a 7-day clinical study of 34 adults with dry skin.
**Based on a clinical trial of 33 adults with damaged skin barriers.
Precision Healing Spray
Soothes flare-ups + calms eczema-prone skin
RESULTS
100%
100% of participants saw immediate improvement in skin barrier function that lasted all day*
97%
experienced instant improvement in hydration**
95%
agreed the spray is non-irritating and gentle on skin**
*Based on a clinical trial of 33 adults with damaged skin barriers.
**Based on a 7-day clinical study of 34 adults with dry skin.
Clinically tested, next-generation formulas that treat eczema's root cause to visibly transform skin.
Backed by Dermatologists
